SUMMARY:

Cephalexin is a widely used antibiotic. It is often used when treating various bacterial infections in both Adults and Pediatrics. Bacterial infections such as Streptococcal Pharyngitis, Uncomplicated Urinary Tract Infections (UTIs), and Bacterial Skin and Skin Structure Infections (SSSIs). There is also an off label indication for Dental Endocarditis Prophylaxis. Cephalexin works by causing bacteria cells to lyse by binding to penicillin-binding proteins (PBPs) thus inhibiting bacterial cell wall synthesis. Caution is to be used in renally impaired patients. Cephalexin appears to be safe for use during pregnancy and when breast-feeding. Common side effects are abdominal pain, nausea, vomiting, and diarrhea. If the suspension is used, after reconstitution the suspension should be refrigerated and discarded after 14 days.