Drug Cards Daily

Episode #43: oxycodone + acetaminophen (Percocet) | Podcast Show Notes
oxycodone (oks I KOE done) + acetaminophen (a seet a MIN oh fen)

Below will be links for the full Podcast and the Drug Card for Percocet along with a brief summary of various points on Percocet. 

QUESTIONS:

  1. True or False. Should naloxone always be prescribed along with Percocet?
  2. True or False. Percocet is indicated only for patients 18 years or older due to the potential for abuse/misuse/addiction.
  3. Select all that apply. Which of the following are appropriate monitoring parameters for Percocet.
    • A). Level of pain relief
    • B). Signs and symptoms of abuse
    • C). Bowel function
    • D). Diarrhea
    • E). Respiratory status

SUMMARY:

Oxycodone+acetaminophen (APAP) is an analgesic combination product also known as Percocet. When dosing for Percocet one should consider also prescribing naloxone if there is a possible risk of opioid overdose or accidental ingestion. It is also very important to note that the lowest effective dose at the shortest effect duration should be used. Dosing for Percocet is based on the oxycodone component but limited by the APAP component. A general dosing range is 2.5-10 mg oxycodone PO q6h prn. Do not exceed 1 gram of APAP in 4 hours and 4 grams of APAP in 24 hours. There are a large amount of black box warnings and it is highly suggested to review them all. Some of note are for addiction/abuse/misuse, respiratory depression, and hepatotoxicity. Patients that should not use this medication are those with severe asthma or similar breathing problems, stomach or intestine blockage, drug or alcohol addiction, or problems with urination/thyroid/pancreas/gallbladder. 

ANSWERS:  

  1. False. It shouldn’t always accompany a Percocet prescription but it is a good idea if there is concern for overdose or accidental ingestion.
  2. False. Although abuse/misuse/addiction is a concern, there is weight based dosing for the pediatric population and is indicated for moderate to severe pain management. 
  3. A, B, C, and E are correct. Constipation is the concern, not diarrhea due to the oxycodone component.
Did you get any wrong? Make sure to listen to this week’s episode and download the free Drug Card for Percocet.

PDF of Drug Card: oxycodone + acetaminophen