Episode #28: loratadine (Claritin) | Podcast Show Notes
loratadine (lor AT a deen)
Below will be links for the full Podcast and the Drug Card for loratadine along with a brief summary of various points on loratadine.
QUESTIONS:
- T or F: Loratadine is a first generation antihistamine that works through inhibiting the H2 receptor.
- What is the typical dosing for adults when treating allergic rhinitis?
- Select all that apply.
- A). Loratadine may increase CNS depressing drugs.
- B). Loratadine may decrease CNS depressing drugs.
- C). Loratadine has no effect on CNS depressing drugs.
- D). All are correct depending on factors such as age, renal function, and hepatic function.
- E). None of the above
- An adult pregnant female presents with symptoms of allergic rhinitis. Which of the following would be appropriate regarding loratadine?
- A). Due to the patient being pregnant, loratadine should not be used.
- B). Due to the patient being pregnant, loratadine is the preferred agent.
- C). Loratadine 5 mg po bid.
- D). Loratadine 5 mg po tid.
- E). A and C are correct.
SUMMARY:
Loratadine is available over the counter and by prescription. Over the counter the most commonly known brand name is Claritin. Loratadine is a second generation antihistamine that works by antagonizing the H1 receptor. The main indications are for allergic rhinitis, conjunctivitis, and urticaria. There are many different dosage forms available from capsule, solution, syrup, tablet, chewable tablet, and disintegrating tablet. When dosing for adults the most common dosing is 10 mg po qd or 5 mg po bid with a max of 10 mg per day. For children 2-6 the chewable tablet or liquid is generally the preferred dosage form and dosed at 5 mg po qd (or 5 mL po qd if solution or syrup). When searching for an antihistamine safe during pregnancy second generation antihistamines are generally considered safe and preferred at the lowest effect dose. Limited side effects but sedation and drowsiness can occur.
ANSWERS:
- False. Loratadine is a “second” generation antihistamine that works through inhibiting the “H1” receptor.
- 10 mg po qd or 5 mg po bid are both correct.
- Only A is correct. Loratadine may increase CNS depressing substances such as alcohol.
- B and C are correct. A second generation antihistamine is appropriate for a pregnant female and 5 mg po bid or 10 mg po qd are appropriate dosing regimens.
PDF of Drug Card: loratadine
