SUMMARY:

Dicyclomine is an antispasmodic anticholinergic agent that is used to treat stomach and intestinal cramping that is often associated with irritable bowel syndrome (IBS). The brand name is Bentyl. There are various dosage forms such as oral and intramuscular solutions but the most commonly used are capsules. The capsules come in a 10 and 20 mg strength. When dosing to treat the abdominal pain associated with IBS, initiate 20 mg po qid for 2 weeks or less. Longer durations of treatment have not proven any additional benefits to the patient. Dicyclomine works by blocking acetylcholine at parasympathetic sites such as the smooth muscle and secretory glands in the central nervous system. This drug is not recommended for children under 6 months old and in the geriatric population due to the risk of serious side effects. The two most common side effects are dizziness and xerostomia (dry mouth). If using antacids, separate usage between the two by using dicyclomine before meals and the antacid after meals.